Propofol Exposure in Pregnant Rats Induces Neurotoxicity and Persistent Learning Deficit in the Offspring

Propofol Exposure in Pregnant Rats Induces Neurotoxicity and Persistent Learning Deficit in the Offspring

Propofol is a general anesthetic widely used in surgical procedures, including those in pregnant women. Preclinical studies suggest that propofol may cause neuronal injury to the offspring of primates if it is administered during pregnancy. However, it is unknown whether those neuronal changes would...

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Bibliographic Details
Main Authors: Ming Xiong, Jing Li, Hussain M. Alhashem, Vasanti Tilak, Anuradha Patel, Sergey Pisklakov, Allan Siegel, Jiang Hong Ye, Alex Bekker
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Brain Sciences
Subjects:
propofol
prenatal exposure
neurotoxicity
learning deficit
offspring
Online Access:http://www.mdpi.com/2076-3425/4/2/356

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http://www.mdpi.com/2076-3425/4/2/356

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