Chromosomal instability associated with adverse outcome: a case report of patient with Nijmegen breakage syndrome and rapidly developed T-NHL with complex karyotype

Chromosomal instability associated with adverse outcome: a case report of patient with Nijmegen breakage syndrome and rapidly developed T-NHL with complex karyotype

Abstract Background Nijmegen breakage syndrome (NBS) is a rare genetic disorder inherited in an autosomal recessive pattern associated with an increased risk of developing lymphoproliferative disorders, mainly non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL). NBS patients are 50 tim...

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Bibliographic Details
Main Authors: Monika Włodarczyk, Monika Lejman
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Cytogenetics
Subjects:
Nijmegen breakage syndrome
Non-Hodgkin lymphoma
Gene
FISH
Microarray
Online Access:http://link.springer.com/article/10.1186/s13039-020-00505-2

Internet

http://link.springer.com/article/10.1186/s13039-020-00505-2

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