Pancreatic Lineage Specifier PDX1 Increases Adhesion and Decreases Motility of Cancer Cells

Pancreatic Lineage Specifier PDX1 Increases Adhesion and Decreases Motility of Cancer Cells

Intercellular interactions involving adhesion factors are key operators in cancer progression. In particular, these factors are responsible for facilitating cell migration and metastasis. Strengthening of adhesion between tumor cells and surrounding cells or extracellular matrix (ECM), may provide a...

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Bibliographic Details
Main Authors: Liya Kondratyeva, Igor Chernov, Eugene Kopantzev, Dmitry Didych, Alexey Kuzmich, Irina Alekseenko, Sergey Kostrov, Eugene Sverdlov
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
pancreatic cancer
PDX1
epithelial-mesenchymal transition
cancer metastasis
cell migration
cell adhesion
Online Access:https://www.mdpi.com/2072-6694/13/17/4390

Internet

https://www.mdpi.com/2072-6694/13/17/4390

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