Dual Targeting to Overcome Current Challenges in Multiple Myeloma CAR T-Cell Treatment

In the era of highly promising novel targeted-immunotherapy strategies for multiple myeloma (MM), the first series of clinical trials with CAR T-cells targeting the plasma cell-specific B-cell maturation antigen (BCMA) have shown excellent response rates. In the long-term, however, MM appears to esc...

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Bibliographic Details
Main Authors: Jort J. van der Schans, Niels W. C. J. van de Donk, Tuna Mutis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01362/full