Dual Targeting to Overcome Current Challenges in Multiple Myeloma CAR T-Cell Treatment
In the era of highly promising novel targeted-immunotherapy strategies for multiple myeloma (MM), the first series of clinical trials with CAR T-cells targeting the plasma cell-specific B-cell maturation antigen (BCMA) have shown excellent response rates. In the long-term, however, MM appears to esc...
Main Authors: | Jort J. van der Schans, Niels W. C. J. van de Donk, Tuna Mutis |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-08-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2020.01362/full |
Similar Items
-
Recent updates on CAR T clinical trials for multiple myeloma
by: Quande Lin, et al.
Published: (2019-11-01) -
Editorial: Exploiting the Immune System to Treat Multiple Myeloma: From Transplantation to Novel Treatment Approaches
by: Niels W. C. J. van de Donk, et al.
Published: (2020-10-01) -
Overcoming Chimeric Antigen Receptor (CAR) Modified T-Cell Therapy Limitations in Multiple Myeloma
by: Estefanía García-Guerrero, et al.
Published: (2020-06-01) -
Multi-antigen-targeted chimeric antigen receptor T cells for cancer therapy
by: Xiao Han, et al.
Published: (2019-11-01) -
Steering CAR T cells to distinguish friend from foe
by: Hillary G. Caruso, et al.
Published: (2019-10-01)