Gene expression noise in a complex artificial toxin expression system.

Gene expression is an intrinsically stochastic process. Fluctuations in transcription and translation lead to cell-to-cell variations in mRNA and protein levels affecting cellular function and cell fate. Here, using fluorescence time-lapse microscopy, we quantify noise dynamics in an artificial oper...

Full description

Bibliographic Details
Main Authors: Alexandra Goetz, Andreas Mader, Benedikt von Bronk, Anna S Weiss, Madeleine Opitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227249