Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians

Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians

The genetic basis for dementias is complex. A common polymorphism in the apolipoprotein E (APOE) gene is considered to be the major risk factor in families with sporadic and late-onset Alzheimer's disease as well as in the general population. The distribution of alleles and genotypes of the APO...

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Bibliographic Details
Main Authors: D.R.S. Souza, M.R. De Godoy, J. Hotta, E.H. Tajara, A.C. Brandão, S. Pinheiro Júnior, W.A. Tognola, J.E. Dos Santos
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2003-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Alzheimer's disease
Vascular dementia
Dementia
Apolipoprotein E
Aging
Genetic polymorphisms
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700013

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700013

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