Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.

Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.

Transcription control at a distance is a critical mechanism, particularly for contiguous genes. The peptidylarginine deiminases (PADs) catalyse the conversion of protein-bound arginine into citrulline (deimination), a critical reaction in the pathophysiology of multiple sclerosis, Alzheimer's d...

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Bibliographic Details
Main Authors: Stéphane Chavanas, Véronique Adoue, Marie-Claire Méchin, Shibo Ying, Sijun Dong, Hélène Duplan, Marie Charveron, Hidenari Takahara, Guy Serre, Michel Simon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18923650/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18923650/?tool=EBI

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