RNA Sequencing Identifies Upregulated Kyphoscoliosis Peptidase and Phosphatidic Acid Signaling Pathways in Muscle Hypertrophy Generated by Transgenic Expression of Myostatin Propeptide

RNA Sequencing Identifies Upregulated Kyphoscoliosis Peptidase and Phosphatidic Acid Signaling Pathways in Muscle Hypertrophy Generated by Transgenic Expression of Myostatin Propeptide

Myostatin (MSTN), a member of the transforming growth factor-β superfamily, plays a crucial negative role in muscle growth. MSTN mutations or inhibitions can dramatically increase muscle mass in most mammal species. Previously, we generated a transgenic mouse model of muscle hypertrophy via the tran...

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Bibliographic Details
Main Authors: Yuanxin Miao, Jinzeng Yang, Zhong Xu, Lu Jing, Shuhong Zhao, Xinyun Li
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:International Journal of Molecular Sciences
Subjects:
myostatin
RNA-sequencing
transgenic mice
muscle hypertrophy
Online Access:http://www.mdpi.com/1422-0067/16/4/7976

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http://www.mdpi.com/1422-0067/16/4/7976

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