Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission.

Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission.

Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study offered the opportunity to compare amplicon-based 454 ultra-deep sequencing (UDS) and allele-sp...

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Bibliographic Details
Main Authors: Andrea Hauser, Claudia Kuecherer, Andrea Kunz, Piotr Wojtek Dabrowski, Aleksandar Radonić, Andreas Nitsche, Stefanie Theuring, Norbert Bannert, Julius Sewangi, Paulina Mbezi, Festo Dugange, Gundel Harms, Karolin Meixenberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4607442?pdf=render

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http://europepmc.org/articles/PMC4607442?pdf=render

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