A novel approach to pharmacodynamic assessment of antimicrobial agents: new insights to dosing regimen design.
Pharmacodynamic modeling has been increasingly used as a decision support tool to guide dosing regimen selection, both in the drug development and clinical settings. Killing by antimicrobial agents has been traditionally classified categorically as concentration-dependent (which would favor less fra...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3017105?pdf=render |