Myeloid-derived Suppressor Cells Elimination by 5-Fluorouracil Increased Dendritic Cell-based Vaccine Function and Improved Immunity in Tumor Mice

Myeloid-derived Suppressor Cells Elimination by 5-Fluorouracil Increased Dendritic Cell-based Vaccine Function and Improved Immunity in Tumor Mice

Myeloid-derived suppressor cells (MDSCs) are capable of suppressing the immune response. 5-Fluorouracil (5-FU) compared to other chemotherapy drugs have shown considerable decreases in the number of MDSCs without visible effects on T, B and natural killer cells, as well as dendritic cells (DCs). DC...

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Bibliographic Details
Main Authors: Najmeh khosravianfar, Jamshid Hadjati, Afshin Namdar, Roobina Boghozian, Morteza Hafezi, Mahboubeh Ashourpour, Nasim Kheshtchin, Mahsa Banitalebi, Reza Mirzaei, Seyed Alireza Razavi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-02-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Dendritic cell
5- Fluorouracil
Myeloid-derived suppressor cell
Tumor
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1331

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https://ijaai.tums.ac.ir/index.php/ijaai/article/view/1331

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