An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies.

An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies.

The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R) contributes to vascular hypertrophy in angiotensin II (ANG II)-induced hypertension, through a mechanism involving reactive oxygen species (...

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Bibliographic Details
Main Authors: Graziela S Ceravolo, Augusto C Montezano, Maria T Jordão, Eliana H Akamine, Tiago J Costa, Ana P Takano, Denise C Fernandes, Maria L Barreto-Chaves, Francisco R Laurindo, Rita C Tostes, Zuleica B Fortes, Renato P Chopard, Rhian M Touyz, Maria Helena C Carvalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219703?pdf=render

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http://europepmc.org/articles/PMC4219703?pdf=render

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