Lipid motif of a bacterial antigen mediates immune responses via TLR2 signaling.

The cross-talk between the innate and the adaptive immune system is facilitated by the initial interaction of antigen with dendritic cells. As DCs express a large array of TLRs, evidence has accumulated that engagement of these molecules contributes to the activation of adaptive immunity. We have ev...

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Bibliographic Details
Main Authors: Amit A Lugade, Anna Bianchi-Smiraglia, Vandana Pradhan, Galina Elkin, Timothy F Murphy, Yasmin Thanavala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3096640?pdf=render