Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies

Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies

After albumin, immunoglobulin G (IgG) are the most abundant proteins in human serum, with IgG1 and IgG3 being the most abundant subclasses directed against protein antigens. The quality of the IgG-Fc-glycosylation has important functional consequences, which have been found to be skewed toward low f...

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Bibliographic Details
Main Authors: Myrthe E. Sonneveld, Carolien A. M. Koeleman, H. Rosina Plomp, Manfred Wuhrer, C. Ellen van der Schoot, Gestur Vidarsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Fc glycosylation
IgG1
IgG3
IgG1 Fc
IgG3 Fc
antibodies
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00129/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00129/full

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