Exoproteome profiling of Trypanosoma cruzi during amastigogenesis early stages.

Chagas disease is caused by the protozoan Trypanosoma cruzi, affecting around 8 million people worldwide. After host cell invasion, the infective trypomastigote form remains 2-4 hours inside acidic phagolysosomes to differentiate into replicative amastigote form. In vitro acidic-pH-induced axenic am...

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Bibliographic Details
Main Authors: Samuel C Mandacaru, Rayner M L Queiroz, Marcos R Alborghetti, Lucas S de Oliveira, Consuelo M R de Lima, Izabela M D Bastos, Jaime M Santana, Peter Roepstorff, Carlos André O Ricart, Sébastien Charneau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225386