Mechanism-Guided Discovery of an Esterase Scaffold with Promiscuous Amidase Activity

The discovery and generation of biocatalysts with extended catalytic versatilities are of immense relevance in both chemistry and biotechnology. An enhanced atomistic understanding of enzyme promiscuity, a mechanism through which living systems acquire novel catalytic functions and specificities by...

Full description

Bibliographic Details
Main Authors: Charlotte Kürten, Bengt Carlberg, Per-Olof Syrén
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Catalysts
Subjects:
Online Access:http://www.mdpi.com/2073-4344/6/6/90