Comparison of Aggregated N-of-1 Trials with Parallel and Crossover Randomized Controlled Trials Using Simulation Studies

Comparison of Aggregated N-of-1 Trials with Parallel and Crossover Randomized Controlled Trials Using Simulation Studies

<i>Background:</i> N-of-1 trials offer an innovative approach to delivering personalized clinical care together with population-level research. While increasingly used, these methods have raised some statistical concerns in the healthcare community. <i>Methods:</i> We discuss...

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Bibliographic Details
Main Authors: J. Walker Blackston, Andrew G. Chapple, James M. McGree, Suzanne McDonald, Jane Nikles
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Healthcare
Subjects:
n-of-1 trial
evidence-based medicine
comparative effectiveness
clinical trial
single-case study
simulation study
statistical methods
Online Access:https://www.mdpi.com/2227-9032/7/4/137

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https://www.mdpi.com/2227-9032/7/4/137

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