A Biochemical and Pharmacological Characterization of Phospholipase A<sub>2</sub> and Metalloproteinase Fractions from Eastern Russell’s Viper (<i>Daboia siamensis</i>) Venom: Two Major Components Associated with Acute Kidney Injury

A Biochemical and Pharmacological Characterization of Phospholipase A<sub>2</sub> and Metalloproteinase Fractions from Eastern Russell’s Viper (<i>Daboia siamensis</i>) Venom: Two Major Components Associated with Acute Kidney Injury

Acute kidney injury (AKI) following Eastern Russell’s viper (<i>Daboia siamensis</i>) envenoming is a significant symptom in systemically envenomed victims. A number of venom components have been identified as causing the nephrotoxicity which leads to AKI. However, the precise mechanism...

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Bibliographic Details
Main Authors: Janeyuth Chaisakul, Orawan Khow, Kulachet Wiwatwarayos, Muhamad Rusdi Ahmad Rusmili, Watcharamon Prasert, Iekhsan Othman, Syafiq Asnawi Zainal Abidin, Mongkon Charoenpitakchai, Wayne C. Hodgson, Lawan Chanhome, Narongsak Chaiyabutr
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Toxins
Subjects:
phospholipase A<sub>2</sub>
venom
nephrotoxicity
Russell’s viper
myotoxicity
kidney
Online Access:https://www.mdpi.com/2072-6651/13/8/521

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https://www.mdpi.com/2072-6651/13/8/521

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