Tryptophan Metabolism Activates Aryl Hydrocarbon Receptor-Mediated Pathway To Promote HIV-1 Infection and Reactivation
Cellular metabolic pathways that are altered by HIV-1 infection may accelerate disease progression. Dysfunction in tryptophan (Trp) metabolism has been observed clinically in association with accelerated HIV-1 pathogenesis, but the mechanism responsible was not known. This study demonstrates that Tr...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-12-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.02591-19 |