A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells.

<h4>Background</h4>The growth of stem cells in in vitro conditions requires optimal balance between signals mediating cell survival, proliferation, and self-renewal. For clinical application of stem cells, the use of completely defined conditions and elimination of all animal-derived mat...

Full description

Bibliographic Details
Main Authors: Kristiina Rajala, Bettina Lindroos, Samer M Hussein, Riikka S Lappalainen, Mari Pekkanen-Mattila, Jose Inzunza, Björn Rozell, Susanna Miettinen, Susanna Narkilahti, Erja Kerkelä, Katriina Aalto-Setälä, Timo Otonkoski, Riitta Suuronen, Outi Hovatta, Heli Skottman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20419109/?tool=EBI