Transcriptome profiles acquired during cell expansion and licensing validate mesenchymal stromal cell lineage genes

Transcriptome profiles acquired during cell expansion and licensing validate mesenchymal stromal cell lineage genes

Abstract Background Mesenchymal stromal cells (MSCs) are rapidly advancing as commercial therapeutics. However, there are still no adequate tools to validate the identity of MSCs and support standardization of MSC-based products. Currently accepted metrics include cell surface marker profiling and t...

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Bibliographic Details
Main Authors: Danielle M. Wiese, Lorena R. Braid
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cell
Transcriptomics
Cell characterization
Molecular profiling
Identity assays
Umbilical cord
Online Access:http://link.springer.com/article/10.1186/s13287-020-01873-7

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http://link.springer.com/article/10.1186/s13287-020-01873-7

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