Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis*s⃞

Lipin-1 deficiency in the mouse causes generalized lipodystrophy, characterized by impaired adipose tissue development and insulin resistance. Lipin-1 expression in differentiating preadipocytes is required for normal expression of adipogenic transcription factors, including peroxisome proliferator-...

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Bibliographic Details
Main Authors: Peixiang Zhang, Lauren O'Loughlin, David N. Brindley, Karen Reue
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520347234