Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis*s⃞
Lipin-1 deficiency in the mouse causes generalized lipodystrophy, characterized by impaired adipose tissue development and insulin resistance. Lipin-1 expression in differentiating preadipocytes is required for normal expression of adipogenic transcription factors, including peroxisome proliferator-...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520347234 |