Enhancing cognate target elution efficiency in gel-free chemical proteomics

Gel-free liquid chromatography mass spectrometry coupled to chemical proteomics is a powerful approach for characterizing cellular target profiles of small molecules. We have previously described a fast and efficient elution protocol; however, altered target profiles were observed. We hypothesised t...

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Bibliographic Details
Main Authors: Branka Radic-Sarikas, Uwe Rix, Alexey Stukalov, Manuela Gridling, André C. Müller, Jacques Colinge, Giulio Superti-Furga, Keiryn L. Bennett
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:EuPA Open Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968515300210