Enhancing cognate target elution efficiency in gel-free chemical proteomics
Gel-free liquid chromatography mass spectrometry coupled to chemical proteomics is a powerful approach for characterizing cellular target profiles of small molecules. We have previously described a fast and efficient elution protocol; however, altered target profiles were observed. We hypothesised t...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-12-01
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Series: | EuPA Open Proteomics |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212968515300210 |