Crystal structure of the atypically adhesive SpaB basal pilus subunit: Mechanistic insights about its incorporation in lactobacillar SpaCBA pili

Crystal structure of the atypically adhesive SpaB basal pilus subunit: Mechanistic insights about its incorporation in lactobacillar SpaCBA pili

To successfully colonize a host or environment, certain genera and species of Gram-positive bacteria have evolved to utilize the so-called sortase-dependent pilus, a long multi-subunit and non-flagellar surface adhesin. One example of this is Lactobacillus rhamnosus GG, a gut-adapted probiotic strai...

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Bibliographic Details
Main Authors: Abhin Kumar Megta, Shivendra Pratap, Abhiruchi Kant, Airi Palva, Ingemar von Ossowski, Vengadesan Krishnan
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Current Research in Structural Biology
Subjects:
Sortase-dependent SpaCBA pili
SpaB basal pilin
Cell-wall anchoring
Mucus adhesion
Lactobacillus rhamnosus GG
Probiotic
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X20300234

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http://www.sciencedirect.com/science/article/pii/S2665928X20300234

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