Decoration of Nanovesicles with pH (Low) Insertion Peptide (pHLIP) for Targeted Delivery

Abstract Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells. We used the pH (low) insertion peptide (pHLIP) for decoration of liposomes and niosomes. pHLIP senses pH...

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Bibliographic Details
Main Authors: Federica Rinaldi, Patrizia N. Hanieh, Elena Del Favero, Valeria Rondelli, Paola Brocca, Mohan C. Pereira, Oleg A. Andreev, Yana K. Reshetnyak, Carlotta Marianecci, Maria Carafa
Format: Article
Language:English
Published: SpringerOpen 2018-12-01
Series:Nanoscale Research Letters
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11671-018-2807-8