EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis

<p>Abstract</p> <p>Background</p> <p>Proteolytic cleavage of the extracellular domain (EpEx) of Epithelial cell adhesion molecule (EpCAM) and nuclear signaling by its intracellular oncogenic domain Ep-ICD has recently been implicated in increased proliferation of cancer...

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Bibliographic Details
Main Authors: MacMillan Christina, Lim Terence, Cao Jun, Ralhan Ranju, Freeman Jeremy L, Walfish Paul G
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/331