miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages

miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages

The Notch pathway plays critical roles in the differentiation and polarized activation of macrophages; however, the downstream molecular mechanisms underlying Notch activity in macrophages remain elusive. Our previous study has identified a group of microRNAs that mediate Notch signaling to regulate...

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Bibliographic Details
Main Authors: Fei Huang, Jun-Long Zhao, Liang Wang, Chun-Chen Gao, Shi-Qian Liang, Dong-Jie An, Jian Bai, Yan Chen, Hua Han, Hong-Yan Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
macrophages
Notch signaling
miR-148a-3p
PTEN
NF-κB
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01327/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01327/full

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