Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma.

Neuroblastoma (NB) is a typical childhood and heterogeneous neoplasm for which efficient targeted therapies for high-risk tumors are not yet identified. The chemokine CXCL12, and its receptors CXCR4 and CXCR7 have been involved in tumor progression and dissemination. While CXCR4 expression is associ...

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Bibliographic Details
Main Authors: Julie Liberman, Hervé Sartelet, Marjorie Flahaut, Annick Mühlethaler-Mottet, Aurélie Coulon, Carine Nyalendo, Gilles Vassal, Jean-Marc Joseph, Nicole Gross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3423387?pdf=render