Esculetin reduces leukotriene B4 level in plasma of rats with adjuvant-induced arthritis

Esculetin reduces leukotriene B4 level in plasma of rats with adjuvant-induced arthritis

Objectives : Esculetin (6,7-dihydroxycoumarin) is a natural coumarin with anti-oxidant, anti-inflammatory and anti-nociceptive activity. It acts as a potent inhibitor of lipoxygenases (5-LOX and 12-LOX) and decreases the production of matrix metalloproteinases (MMP-1, MMP-3 and MMP-9). Because both...

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Bibliographic Details
Main Authors: Przemysław Rzodkiewicz, Emilia Gąsińska, Michał Gajewski, Magdalena Bujalska-Zadrożny, Dariusz Szukiewicz, Sławomir Maśliński
Format: Article
Language:English
Published: Termedia Publishing House 2016-10-01
Series:Rheumatology
Subjects:
esculetin
treatment
adjuvant-induced inflammation
leukotriene B4
Online Access:http://www.termedia.pl/Esculetin-reduces-leukotriene-B4-level-in-plasma-of-rats-with-adjuvant-induced-arthritis,18,28366,1,1.html

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http://www.termedia.pl/Esculetin-reduces-leukotriene-B4-level-in-plasma-of-rats-with-adjuvant-induced-arthritis,18,28366,1,1.html

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