The Accuracy and Bias of Single-Step Genomic Prediction for Populations Under Selection

In single-step analyses, missing genotypes are explicitly or implicitly imputed, and this requires centering the observed genotypes using the means of the unselected founders. If genotypes are only available for selected individuals, centering on the unselected founder mean is not straightforward. H...

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Bibliographic Details
Main Authors: Wan-Ling Hsu, Dorian J. Garrick, Rohan L. Fernando
Format: Article
Language:English
Published: Oxford University Press 2017-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.043596