WDHD1 facilitates G1 checkpoint abrogation in HPV E7 expressing cells by modulating GCN5

WDHD1 facilitates G1 checkpoint abrogation in HPV E7 expressing cells by modulating GCN5

Abstract Background Genomic instability is a hallmark of cancer. The G1 checkpoint allows cells to repair damaged DNA that may lead to genomic instability. The high-risk human papillomavirus (HPV) E7 gene can abrogate the G1 checkpoint, yet the mechanism is still not fully understood. Our recent stu...

Full description

Bibliographic Details
Main Authors: Yunying Zhou, Fengyan Pei, Mingyu Ji, Fang Zhang, Yingshuo Sun, Qianqian Zhao, Xiao Wang, Yatian Hong, Juanjuan Tian, Yunshan Wang, Jason J. Chen
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Cancer
Subjects:
WDHD1
GCN5
P-Akt
G1 arrest
HPV
Online Access:http://link.springer.com/article/10.1186/s12885-020-07287-1

Internet

http://link.springer.com/article/10.1186/s12885-020-07287-1

Similar Items