Immature dengue virus: a veiled pathogen?

Cells infected with dengue virus release a high proportion of immature prM-containing virions. In accordance, substantial levels of prM antibodies are found in sera of infected humans. Furthermore, it has been recently described that the rates of prM antibody responses are significantly higher in pa...

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Bibliographic Details
Main Authors: Izabela A Rodenhuis-Zybert, Hilde M van der Schaar, Júlia M da Silva Voorham, Heidi van der Ende-Metselaar, Huan-Yao Lei, Jan Wilschut, Jolanda M Smit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2798752?pdf=render