Extracellular proteolysis in structural and functional plasticity of mossy fiber synapses in hippocampus

Brain is continuously altered in response to experience and environmental changes. One of the underlying mechanisms is synaptic plasticity, which is manifested by modification of synapse structure and function. It is becoming clear that regulated extracellular proteolysis plays a pivotal role in the...

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Bibliographic Details
Main Authors: Grzegorz eWiera, Jerzy W Mozrzymas
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
TPA
MMP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00427/full