Melamine promotes calcium crystal formation in three-dimensional microfluidic device

Abstract Melamine, which induces proximal tubular (PT) cell damage has a greater nephrotoxic effect when combined with cyanuric and uric acids; however, it is unknown whether such effect can stimulate calcium phosphate (CaP)/calcium oxalate (CaOx) stone formation. Here, we show that melamine acts as...

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Bibliographic Details
Main Authors: Farai Gombedza, Sade Evans, Samuel Shin, Eugenia Awuah Boadi, Qian Zhang, Zhihong Nie, Bidhan C. Bandyopadhyay
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-37191-5