Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart

How coronary vessels develop and respond to injury is not fully understood. Here, the authors use murine enhancer:reporter models to identify three transcriptional pathways active in different parts of coronary vasculature. These also contribute to neovascularization in the injured neonatal, but not...

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Bibliographic Details
Main Authors: Sophie Payne, Mala Gunadasa-Rohling, Alice Neal, Andia N. Redpath, Jyoti Patel, Kira M. Chouliaras, Indrika Ratnayaka, Nicola Smart, Sarah De Val
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10710-2