Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.

HIV-1 reservoirs preclude virus eradication in patients receiving highly active antiretroviral therapy (HAART). The best characterized reservoir is a small, difficult-to-quantify pool of resting memory CD4(+) T cells carrying latent but replication-competent viral genomes. Because strategies targeti...

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Bibliographic Details
Main Authors: Susanne Eriksson, Erin H Graf, Viktor Dahl, Matthew C Strain, Steven A Yukl, Elena S Lysenko, Ronald J Bosch, Jun Lai, Stanley Chioma, Fatemeh Emad, Mohamed Abdel-Mohsen, Rebecca Hoh, Frederick Hecht, Peter Hunt, Ma Somsouk, Joseph Wong, Rowena Johnston, Robert F Siliciano, Douglas D Richman, Una O'Doherty, Sarah Palmer, Steven G Deeks, Janet D Siliciano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3573107?pdf=render