A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells.

A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells.

Accumulating data indicate that cancer stem cells contribute to tumor chemoresistance and their persistence alters clinical outcome. Our previous study has shown that ovarian cancer may be initiated by ovarian cancer initiating cells (OCIC) characterized by surface antigen CD44 and c-KIT (CD117). It...

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Bibliographic Details
Main Authors: Frank H C Cheng, Baltazar D Aguda, Je-Chiang Tsai, Marek Kochańczyk, Jora M J Lin, Gary C W Chen, Hung-Cheng Lai, Kenneth P Nephew, Tzy-Wei Hwang, Michael W Y Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4278842?pdf=render

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http://europepmc.org/articles/PMC4278842?pdf=render

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