A concise enantioselective synthesis of the guaiane sesquiterpene (−)-oxyphyllol
(−)-Oxyphyllol was prepared in only 4 steps from an epoxy enone that already served as an intermediate for the total synthesis of the anticancer guaiane (−)-englerin A. A regio- and diastereoselective Co(II)-catalyzed hydration of the olefin and a transannular epoxide opening were used as the key re...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2013-10-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.9.239 |