MicroRNA-224 is Readily Detectable in Urine of Individuals with Diabetes Mellitus and is a Potential Indicator of Beta-Cell Demise

MicroRNA-224 is Readily Detectable in Urine of Individuals with Diabetes Mellitus and is a Potential Indicator of Beta-Cell Demise

MicroRNA (miRNA) are a class of non-coding, 19–25 nucleotide RNA critical for network-level regulation of gene expression. miRNA serve as paracrine signaling molecules. Using an unbiased array approach, we previously identified elevated levels of miR-224 and miR-103 to be associated with a monogenic...

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Bibliographic Details
Main Authors: Siobhán Bacon, Britta Engelbrecht, Jasmin Schmid, Shona Pfeiffer, Ross Gallagher, Ailbhe McCarthy, Marie Burke, Caoimhín Concannon, Jochen H. M. Prehn, Maria M. Byrne
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Genes
Subjects:
diabetes associated microRNA
miR-103
miR-224
urinary biomarker
insulin secretion
Online Access:http://www.mdpi.com/2073-4425/6/2/399

Internet

http://www.mdpi.com/2073-4425/6/2/399

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