Utilizing twins as controls for non-twin case-materials in genome wide association studies.

Utilizing twins as controls for non-twin case-materials in genome wide association studies.

Twin registries around the globe have collected DNA samples from large numbers of monozygotic and dizygotic twins. The twin sample collections are frequently used as controls in disease-specific studies together with non-twins. This approach is unbiased under the hypothesis that twins and singletons...

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Bibliographic Details
Main Authors: Andrea Ganna, Alfredo Ortega-Alonso, Aki Havulinna, Veikko Salomaa, Jaakko Kaprio, Nancy L Pedersen, Patrick F Sullivan, Erik Ingelsson, Christina M Hultman, Patrik K E Magnusson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3858365?pdf=render

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http://europepmc.org/articles/PMC3858365?pdf=render

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