Microglia/Astrocytes–Glioblastoma Crosstalk: Crucial Molecular Mechanisms and Microenvironmental Factors

Microglia/Astrocytes–Glioblastoma Crosstalk: Crucial Molecular Mechanisms and Microenvironmental Factors

In recent years, the functions of glial cells, namely, astrocytes and microglia, have gained prominence in several diseases of the central nervous system, especially in glioblastoma (GB), the most malignant primary brain tumor that leads to poor clinical outcomes. Studies showed that microglial cell...

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Bibliographic Details
Main Authors: Diana Matias, Joana Balça-Silva, Grazielle C. da Graça, Caroline M. Wanjiru, Lucy W. Macharia, Carla Pires Nascimento, Natalia R. Roque, Juliana M. Coelho-Aguiar, Cláudia M. Pereira, Marcos F. Dos Santos, Luciana S. Pessoa, Flavia R. S. Lima, Alberto Schanaider, Valéria P. Ferrer, Tania Cristina Leite de Sampaio e Spohr, Vivaldo Moura-Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
glioblastoma
astrocytes
microglia
crosstalk
cytokines
molecular mechanisms
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00235/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00235/full

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