Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome.

Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome.

In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH. Their particular characteristics make VHHs interesting tools for drug-delivery, passive immunotherapy and hig...

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Bibliographic Details
Main Authors: Soraya S Pereira, Leandro S Moreira-Dill, Michelle S S Morais, Nidiane D R Prado, Marcos L Barros, Andrea C Koishi, Giovanny A C A Mazarrotto, Giselle M Gonçalves, Juliana P Zuliani, Leonardo A Calderon, Andreimar M Soares, Luiz H Pereira da Silva, Claudia N Duarte dos Santos, Carla F C Fernandes, Rodrigo G Stabeli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4171512?pdf=render

Internet

http://europepmc.org/articles/PMC4171512?pdf=render

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