miR-1296-5p decreases ERBB2 expression to inhibit the cell proliferation in ERBB2-positive breast cancer

miR-1296-5p decreases ERBB2 expression to inhibit the cell proliferation in ERBB2-positive breast cancer

Abstract Background The tumor suppressive role of miR-1296 is observed in triple negative breast cancer (TNBC). However, the effect of miR-1296-5p in ERBB2-positive breast cancers remains obscure. Methods Whether ERBB2 was the target gene of the miR-1296-5p was predicted by online software, and dete...

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Bibliographic Details
Main Authors: Gang Chen, Mingfeng He, Yin Yin, Ting Yan, Wenfang Cheng, Zebo Huang, Lan Zhang, Huo Zhang, Ping Liu, Wei Zhu, Yichao Zhu
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cancer Cell International
Subjects:
miR-1296-5p
ERBB2
Breast cancer
Proliferation
mTORC1
Online Access:http://link.springer.com/article/10.1186/s12935-017-0466-y

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http://link.springer.com/article/10.1186/s12935-017-0466-y

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