Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow–derived counterparts

In this study, we show that matrix dense cortical bone is the more potent compartment of bone than bone marrow as a stromal source for mesenchymal stem cells as isolated from adult rats. Lineage-depleted cortical bone-mesenchymal stem cells demonstrated >150-fold enrichment of colony forming unit...

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Bibliographic Details
Main Authors: Daniel Blashki, Matthew B Murphy, Mauro Ferrari, Paul J Simmons, Ennio Tasciotti
Format: Article
Language:English
Published: SAGE Publishing 2016-08-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731416661196