Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic multi-organ debilitating autoimmune disease, which mainly afflicts women in the reproductive years. A complex interaction of genetics, environmental factors and hormones result in the breakdown of immune tolerance to “self” leading to damage and destru...

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Bibliographic Details
Main Authors: Takayuki Katsuyama, George C. Tsokos, Vaishali R. Moulton
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
SLE
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01088/full