Integrating Pharmacokinetics Study, Network Analysis, and Experimental Validation to Uncover the Mechanism of Qiliqiangxin Capsule Against Chronic Heart Failure

Objectives: The purpose of this study was to propose an integrated strategy for investigating the mechanism of Qiliqiangxin capsule (QLQX) to treat chronic heart failure (CHF).Methods: Pharmacokinetics analysis was performed to screen the active components of QLQX using high-performance liquid chrom...

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Bibliographic Details
Main Authors: Yu Zhang, Mingdan Zhu, Fugeng Zhang, Shaoqiang Zhang, Wuxun Du, Xuefeng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01046/full