Simultaneous expression of displayed and secreted antibodies for antibody screen.

Simultaneous expression of displayed and secreted antibodies for antibody screen.

The display of full-length antibody on the cell surface was achieved by fusing a transmembrane domain of the platelet-derived growth factor receptor (PDGFR) to the C-terminus of the heavy chain constant region. We also incorporated a furin cleavage site between the constant region and PDGFR transmem...

Full description

Bibliographic Details
Main Authors: Yuanping Zhou, Junjie Wang, Ivan Zhou, Haibo Lou, Chang-Zheng Li, Zhen-Rui Chen, Zhe-Huan Zhang, Shuwen Liu, Shuguang Wu, Wanlong Tan, Shibo Jiang, Chen Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823846?pdf=render

Internet

http://europepmc.org/articles/PMC3823846?pdf=render

Similar Items