Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases

Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases

Effective treatments for neurodegenerative diseases need to be developed. MiR132 is abundantly expressed in the brain, and it modulates neuron morphology and plays a key role in maintaining neuron survival. Regulating miR132 can effectively improve the symptoms of Alzheimer’s disease. It can also re...

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Bibliographic Details
Main Authors: Yu Su, Bixi Sun, Xiaoshu Gao, Xinyue Dong, Lanbo Fu, Yingxin Zhang, Zhulin Li, Yue Wang, Hongyu Jiang, Bing Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
neurodegenerative diseases
MiR132
nose to brain delivery
nanoparticles
wheat germ agglutinin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01165/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01165/full

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