Reduction of natural killer but not effector CD8 T lymphocytes in three consecutive cases of severe/lethal H1N1/09 influenza A virus infection.

BACKGROUND:The cause of severe disease in some patients infected with pandemic influenza A virus is unclear. METHODOLOGY/PRINCIPAL FINDINGS:We present the cellular immunology profile in the blood, and detailed clinical (and post-mortem) findings of three patients with rapidly progressive infection,...

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Bibliographic Details
Main Authors: Laura Denney, Celia Aitken, Chris Ka-Fai Li, Eleri Wilson-Davies, Wai Ling Kok, Colin Clelland, Kevin Rooney, Duncan Young, Tao Dong, Andrew J McMichael, William F Carman, Ling-Pei Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2872666?pdf=render